One enantiomer caused the desirable sedative effects, while the other, unavoidably present in equal quantities, caused birth defects.. There's no cure for psoriasis, but a range of treatments can improve symptoms and the appearance of skin patches. [4] It is not clear which are the people who might need a second injection at the outset. In most cases, the first treatment used will be a topical treatment, such as vitamin D analogues or topical corticosteroids. These cookies may also be used for advertising purposes by these third parties. If the area around the unconscious person seems safe, approach them and begin CPR. [115] At its core is a repurposed insulin autoinjector. [4][5] Minor adverse effects from epinephrine include tremors, anxiety, headaches, and palpitations. To help prevent infection, apply an antibiotic ointment and loosely cover the burn with clean gauze. Thank you for taking the time to confirm your preferences. You may be referred to a specialist in diagnosing and treating skin conditions (dermatologist) if your doctor is uncertain about your diagnosis, or if your condition is severe. It looks like BioWare is jumping on the bandwagon and using the once-unofficial Dragon Age Day to drop news about the narrative-driven RPG franchise. If the product you applied at the previous diaper change is clean, leave it in place and add another layer on top of it. It can cause more damage. They realized the inconveniences of carrying bulky autoinjectors and decided to come up with a new device to address the problems while they were in college. To cover and protect larger wounds, you might need to apply a clean gauze pad or roller bandage. OR Despite Christianity's designation as the official religion of the Empire, Augustine declared its message to be spiritual rather than political. If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. [24][25][26] In 2005, it sold the product to Verus Pharmaceuticals,[24] which launched the product the same year. An epinephrine autoinjector (or adrenaline autoinjector, also known by the trademark EpiPen) is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. Newborns at increased risk for gonococcal ophthalmia include those who did not receive ophthalmic prophylaxis and whose mothers had no prenatal care, have a history of STIs during pregnancy, or have a history of substance misuse. Wound care management products for the treatment of acute and chronic wounds, including leg, diabetic and pressure ulcers, burns and post-operative wounds. Job Search Tools ", "FDA-2015-P-0181: Requests that the FDA take certain actions with respect to abbreviated new drug application (ANDA) 90-589, submitted by Teva Pharmaceuticals (Teva), for an epinephrine auto-injector". Ocular prophylaxis for gonococcal ophthalmia neonatorum has a long history of preventing sight-threatening gonococcal ocular infections. Doctrine of Witness, that Jews received prophecy predicting Jesus, and that Jews are dispersed among the nations to provide independent testimony of the Hebrew Scriptures. Possible triggers of psoriasis includean injury to your skin, throat infections and using certain medicines. Pharmacology is the science that deals with the study of Saving Lives, Protecting People, Sexually Transmitted Infections Treatment Guidelines, 2021, National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Retesting After Treatment to Detect Repeat Infections, HIV Infection: Detection, Counseling, and Referral, Diseases Characterized by Genital, Anal, or Perianal Ulcers, Neurosyphilis, Ocular Syphilis, and Otosyphilis, Syphilis Among Persons with HIV Infection, Managing Persons Who Have a History of Penicillin Allergy, Diseases Characterized by Urethritis and Cervicitis, Gonococcal Infections Among Adolescents and Adults, Gonococcal Infections Among Infants and Children, Vulvovaginal Itching, Burning, Irritation, Odor or Discharge, Terms and Abbreviations Used in This Report, U.S. Department of Health & Human Services, screening pregnant women at risk (e.g., women aged <25 years and those aged 25 years who have a new sex partner, more than one sex partner, a sex partner with concurrent partners, a sex partner who has an STI, or live in a community with high rates of gonorrhea) for, retesting pregnant women in the third trimester who initially tested negative but remained at increased risk for acquiring infection (e.g., women aged <25 years and those aged 25 years who have a new sex partner, more than one sex partner, a sex partner with concurrent partners, a sex partner who has an STI, or live in a community with high rates of gonorrhea); and. The book was in response to allegations that Christianity brought about the decline of Rome and is considered one of Augustine's most important works, standing alongside The Confessions, The Enchiridion, On Christian Doctrine, and On the Trinity. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Petroleum jelly and zinc oxide are the time-proven ingredients in many diaper rash products. [31] Mylan had maintained about a 90% market share since it had acquired the product, and had continually raised the price of EpiPens starting in 2009: in 2009, the wholesale price of two EpiPens was about $100; by July 2013, the price was about $265; in May 2015, it was around $461; and in May 2016, the price rose again to around $609,[30] around a 500% jump from the price in 2009. [1][4] The rate of unintentional injections using these devices is unknown but a 2009 review found that the rate is increasing. Warnings For rectal use only. It is most often used for the treatment of anaphylaxis. Press Release: Impax Completes Acquisition Of Tower Holdings, Inc. And Lineage Therapeutics Inc. "Epinephrine self-injectable - Medeca Pharma AB - AdisInsight", "Emerade, 500 micrograms, solution for injection in pre-filled pen - Summary of Product Characteristics (SPC) - (eMC)", "Valeant Form 10-K For the fiscal year ended December 31, 2015", "Allerject epinephrine auto-injectors recalled by drugmaker Sanofi", "Updated: Sanofi US Issues Voluntary Nationwide Recall of All Auvi-Q Due to Potential Inaccurate Dosage Delivery", "French pharma giant vacates deal with Shockoe Slip firm", "Sanofi abandoning Auvi-Q after dosage problems led to total recall", "Cost Jumps Nearly 500-Percent For Life-Saving EpiPens", "People With Food Allergies Say Life-Saving Drug Too Expensive", "Mylan to Launch Cheaper Generic EpiPen Alternative", "Mylan's EpiPen School Sales Trigger N.Y. Neonates who have DGI should be managed in consultation with an infectious disease specialist. [11] In 2016, Robinson and Lareau published a similar technique adapted to used AuviQ autoinjectors. [64] Lineage was a wholly owned subsidiary of Amedra that had acquired the rights to the Adrenaclick authorized generic from Greenstone/Pfizer. [7] Unintentional injections are delivered to a finger or thumb around 90% of the time; they cause intense pain locally but usually completely resolve. Over-the-counter pain relievers can help relieve pain. Infantile seborrhoeic dermatitis (also known as seborrhoeic eczema) is a common skin condition seen in infants, which appears before the age of 3 months and usually resolves by 6-12 months. Gonococcal ophthalmia is strongly suspected when intracellular gram-negative diplococci are identified on Gram stain of conjunctival exudate, justifying presumptive treatment for gonorrhea after appropriate cultures and antimicrobial susceptibility testing for N. gonorrhoeae are performed. We've updated our privacy policy. When anaphylaxis is suspected, epinephrine solution should be given as soon as possible as an intramuscular injection, in the middle of the outer side of the thigh, which corresponds to the A GP might suggest using an antibiotic cream or ointment that you rub on your eyelid if your blepharitis does not clear up after cleaning your eyelids regularly. All information these cookies collect is aggregated and therefore anonymous. [85], On 5 September 2017, FDA posted a warning letter to the manufacturer, Meridian Medical Technologies. [63] and at the same time, Lineage Therapeutics launched its authorized generic version of Adrenaclick. If you encounter an emergency situation, follow these three basic steps: Look for anything that might be dangerous, like signs of fire, falling debris, or violent people. Main principles of clinical pharmacolo General Princples of Pharmacology_Approach to Learning Pharmacology, Introduction of Veterinary pharmacology Somaliland Dr.Osman Abdulahi Farah, Mahatma Gandhi Medical College & Hospital, Introduction Biochemistry for BPT Students, Lecture 2 adithan diuretics july 29, 2016 mgmcri, Unit-1: General pharmacology :Introduction to pharmacology, Seminar on routes of drug administratin and biotranformation, Microbiology Introduction For Nursing Students, Anti arrhythmic drug for B. Sc Nursing Students, Anti-hypertensive drugs for Nursing Students, Group-4 Youth in Community Action Cyrha Group - Copy.pptx, Module 4 Developmental Stages in Middle and Late Adolescence.pptx, Atomic Absorption Spectroscopy RESEARCH TECHNIQUES IN ANIMAL NUTRITION.pptx, Final Presentation Human Services Administration, No public clipboards found for this slide. To treat itching or pain from the sting, consider applying calamine lotion or a paste of baking soda and water to the area several times a day. [102], The EpiPen, manufactured by Meridian Medical Technologies, and marketed by Mylan, has dominated the market. To help prevent infection, apply an antibiotic ointment and loosely cover the burn with clean gauze. August 14, 2012, National Council for Prescription Drug Programs May 2013, Carly Helfand for FiercePharma Mar 1, 2016, Learn how and when to remove this template message, National Association of State Boards of Education, "Anaphylaxis in children: current understanding and key issues in diagnosis and treatment", "Better training tools recommended to support patients using adrenaline auto-injectors", "Brothers Develop New Device to Halt Allergy Attacks", "Retrieval of Additional Epinephrine from Auto-Injectors", "Novel Technique for Epinephrine Removal in New Generation Autoinjectors", "EpiPen inventor helped millions and died in obscurity", Press Release: King Pharmaceuticals to Acquire Meridian Medical Technologies, "EpiPen Recall PointsTo Broader Concerns", Press Release: Meridian Announces Launch Of New EpiPen 2-Pak, Spokane firm sells rights to auto-injector, Approval History NDA 020800 - Twinject and Adrenaclick, "Verus Pharmaceuticals Announces U.S. [30] Heather Bresch, Mylan's CEO, saw an opportunity to increase sales in the US through marketing and advocacy, and the company launched a marketing campaign to increase awareness of the dangers of anaphylaxis for people with severe allergies that made the EpiPen brand as identified with epinephrine autoinjectors as Kleenex is for facial tissue; the company also successfully lobbied the FDA to broaden the label to include risk of anaphylaxis and in parallel, successfully lobbied Congress to generate legislation making EpiPens available in public places like defibrillators are, and hired the same people that Medtronic had worked with on defibrillator legislation to do so. The new device also has retractable needle and automated voice instructions to assist the users on how to correctly use the autoinjectors. Find Your Next Job. [92], As of 2015, the following epinephrine autoinjectors were available in various parts of Europe: Adrenalina WZF, Adrenaline (epinephrine) 1 in 1000 solution for injection BP auto-injector, Altellus, Anapen, Emerade, EpiPen, Fastjekt, FastPen, and Jext. If the scene is safe, assess the condition of the sick or injured person. Theycan offer advice and further treatment if necessary. Stop use and ask your doctor if bleeding occurs condition worsens or does not improve within 7 days redness, irritation, swelling, pain or other If you buy through links on this page, we may earn a small commission. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Gayle Conelly Manchin, mother of Mylan's CEO, Heather Bresch, had become president of the association in 2010, and shortly after had discussed donations from her "daughter's company" to the association. God then separated the light from the darkness. Positive Gram-stained smears of abscess exudate, CSF, or joint aspirate provide a presumptive basis for initiating treatment for N. gonorrhoeae. [85] Questions had been raised by Congress and others about why EpiPen had been classified as a generic rather a proprietary product in the program since 1997; generic drugs have lower rebates (13%) than proprietary drugs (23%), and price hikes for generic drugs cannot be passed onto states, and a common form of pharmaceutical fraud involves misclassifying proprietary drugs as generic under the program. Home Page: Journal of Investigative Dermatology - jidonline.org Cefotaxime 100 mg/kg body weight IV or IM as a single dose can be administered for those neonates unable to receive ceftriaxone because of simultaneous administration of IV calcium. Speak to a GP or your healthcare team if you have psoriasis and youhave any concerns about your physical and mental wellbeing. Drug is a substance used in the diagnosis ,prevention or Gently but firmly wrap the bandage around the injured limb or body part, covering the wound. Free access to premium services like Tuneln, Mubi and more. sja.org.uk/sja/first-aid-advice/first-aid-techniques/how-to-put-on-a-bandage.aspx, redcross.org/get-help/how-to-prepare-for-emergencies/anatomy-of-a-first-aid-kit.html, emergencycareforyou.org/campaigns/until-help-arrives/#sm.00016eaqii12gtfm5r42x3mm650ec, Full-Thickness Burns Are a Life-Threatening Injury That Require Medical Attention, Why Every Anaphylactic Reaction Requires a Trip to the Emergency Room, Gunshot Wound: First Aid, Recovery, and Outlook, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, Beat the Heat with a Cold Bath: 8 Tips for a Refreshing Dip, 8 Expert Tips to Stay Safe During Record Summer Heatwaves. Take a moment now to learn about other strategies to help someone with heat exhaustion or heatstroke recover. She is variously associated with crossroads, entrance-ways, night, light, magic, witchcraft, the Moon, knowledge of herbs and poisonous plants, graves, ghosts, Daily cleaning with soap and water, application of an antibiotic ointment and a dressing are all that is necessary. Cefotaxime 100 mg/kg body weight IV or IM as a single dose can be administered for those neonates unable to receive ceftriaxone because of simultaneous administration of IV calcium. The brothers split to study different fields with a shared goal to create a new device. If your safety is at risk, remove yourself from the area and call for help. This also provides pain relief when thickened nails cause pressure-related pain.. THE author of the following autobiography is personally known to me, and her conversation and manners inspire me with confidence. Note - a "505(b)(2)" is a kind of new drug application that allows the applicant to rely, John Reid Blackwell for the Richmond Times-Dispatch. 1 The song of songs, which is Solomon's.. 2 Let him kiss me with the kisses of his mouth: for thy love is better than wine.. 3 Because of the savour of thy good ointments thy name is as ointment poured forth, therefore do the virgins love thee.. 4 Draw me, we will run after thee: the king hath brought me into his chambers: we will be glad and rejoice in thee, we will remember thy love Definitions and general purpose. Less severe manifestations include rhinitis, vaginitis, urethritis, and scalp infection at sites of previous fetal monitoring. On brown, black and white skin the patches can look pink or red, and the scales white or silvery. If you suspect the sick or injured person needs emergency medical care, tell a nearby person to call 911 or the local number for emergency medical services. [86][87], On 16 August 2018 the FDA approved the first generic EpiPen from Teva Pharmaceuticals. This is a potentially life-threatening condition and medical emergency. Book V: a refutation of the doctrine of fate and an explanation of the Christian doctrine of free will and its consistency with God's omniscience. [31], In March 2016, Teva's ANDA for a generic EpiPen, which had already faced several delays, was rejected by the FDA. DRUG: Drug is a substance used in the The bandage should be wrapped firmly enough to stay put, but not so tightly that it cuts off blood flow. [22] Kaplan continued to improve his designs over the years, filing for example US Patent 6,767,336 in 2003. If someone has a serious injury or illness, they should receive follow-up care from a medical professional. To build on the information you learn here, considering taking a first aid course. The word Pharmacology is derived from Greek If prophylaxis is delayed (i.e., not administered in the delivery room), a monitoring system should be established to ensure that all newborns receive prophylaxis <24 hours after delivery. Pharmacology Introduction for Nursing Students. It appears that you have an ad-blocker running. [4] The intramuscular route is preferred over subcutaneous administration because the latter may have delayed absorption. [20], In 2001 Meridian and Dey introduced a two-pack version of the EpiPen; at that time the device had $23.9 million in annual sales and accounted for 75% of the market in the United States. Ointments and eye drops: If the cause of the swollen eye is Conjunctivitis, you may be able to treat it with ointments or eye drops. Could a cold bath be the key to beating rising temperatures? Book XIII: teaching that death originated as a penalty for Adam's sin, the. [50], In 2010, Pfizer and King sued Novartis' Sandoz generic unit for patent infringement after Sandoz submitted an ANDA to sell a generic EpiPen. INTRODUCTION BY THE EDITOR. Book XIX: the end of the two cities, and the happiness of the people of Christ. It's important for a pressure bandage to not be too tight. [36], King was acquired by Pfizer in 2010 for $3.6 billion in cash. [80] The last price increase sparked widespread outrage in the late summer as parents prepared to send their children back to school and went to pharmacies to get new EpiPens. Book XXII: the eternal happiness for the saints and explanations of the resurrection of the body. [31], Mylan's efforts to maintain its market dominance were aided when Sanofi's competing product was recalled in November 2015 and further when Teva's generic competitor was rejected by the FDA in March 2016. Ceftriaxone 2550 mg/kg body weight/day IV or IM in a single daily dose for 7 days, with a duration of 1014 days if meningitis is documented, Cefotaxime 25 mg/kg body weight IV or IM every 12 hours for 7 days, with a duration of 1014 days if meningitis is documented. Press Releases Building Stronger Pandemic Preparedness With Infectious Disease Modelling Dec 07-2022 ; Blog Post The Fight for $15: How Increasing the Minimum Wage Can Close the Racial Wealth Gap Dec 07-2022 ; Press Releases The Rockefeller Foundation and Digital Square at PATH Commit $5M to Strengthening Data-Driven Health Systems & Global Immunizations Learn to make a splint on the go with these detailed step-by-step instructions. Michael Smith, W3C HTML Activity Lead Last edited: $Date: 2016/09/07 14:16:54 $ Cookies used to make website functionality more relevant to you. Tap here to review the details. Applying lidocaine or an aloe vera gel or cream can also reduce discomfort from minor burns. Introduction to Pharmacology for Nursing Students 1. Mothers who have gonorrhea and their sex partners should be evaluated, tested, and presumptively treated for gonorrhea (see Gonococcal Infection Among Adolescents and Adults). In this war, God moves (by divine intervention, Providence) those governments, political/ideological movements and military forces aligned (or aligned the most) with the Catholic Church (the City of God) in order to oppose by all meansincluding militarythose governments, political/ideological movements and military forces aligned (or aligned the most) with the Devil (the City of the World). treatment of disease. The Lord is the goal of human history the focal point of the longings of history and of civilization, the center of the human race, the joy of every heart and the answer to all its yearnings. Follow-up examination is not required. For some it's just a minor irritation, but for others it can have a big impact on their quality of life. [79], In 2015 Mylan had about $1.5 billion in sales of EpiPens, which accounted for 40% of Mylan's profit. An official publication of the American Academy of Allergy, Asthma, and Immunology, The Journal of Allergy and Clinical Immunology brings timely clinical papers, instructive case reports, and detailed examinations of state-of-the-art equipment and techniques to clinical allergists, immunologists, dermatologists, internists, and other physicians concerned The book presents human history as a conflict between what Augustine calls the Earthly City (often colloquially referred to as the City of Man, but never by Augustine) and the City of God, a conflict that is destined to end in victory for the latter. Wear protective equipment, such as nitrile or vinyl gloves when treating someone with an open wound or a breathing barrier when performing rescue breathing. Last medically reviewed on November 5, 2018. But there is a fly in the ointment. introduction in clinical pharmacology. [23], In 2003, Hollister-Stier received approval from the FDA to market an epinephrine autoinjector called Twinject that could deliver two shots of epinephrine, which it had spent ten years developing. When using this product do not use this product with an applicator if the introduction of the applicator into the rectum causes additional pain. For some people, a bee sting is a medical emergency. Mothers of newborns with ophthalmia neonatorum caused by N. gonorrhoeae should be evaluated, tested, and presumptively treated for gonorrhea, along with their sex partners (see Gonococcal Infection Among Adolescents and Adults). Wound care management products and treatment solutions that address the human and economic cost of wounds. Shop the best CBD Gummies online from Hemp Bombs made in the U.S. Buy CBD Gummies for sale in high potency, sleep, immunity and botanical blends. 2005-2022 Healthline Media a Red Ventures Company. In many cases, you can use an adhesive bandage to cover minor cuts, scrapes, or burns. INTRODUCTION TO PHARMACOLOGY DEFINITION: Pharmacology is the science that deals with the study of drugs and their interaction with the living systems. You can buy preassembled first aid kits from many first aid organizations, pharmacies, or outdoor recreation stores. [33] The devices deliver about $1 worth of drug. He then helped to slightly alter the technology in order to create EpiPen's current design. As heatwaves spread, these expert tips will help you and loved ones stay safe. If youre alone, make the call yourself. Book IV: a proof that the power and long duration of the Roman empire was due not to the pagan gods but to the Christian God. You can review and change the way we collect information below. distribution ,metabolism and excretion of drugs,i.e what the Feb 1, 2013, Staff, Monthly Prescribing Reference. By whitelisting SlideShare on your ad-blocker, you are supporting our community of content creators. [31] Those profits were also due in part to Mylan's continually raising the price of EpiPens starting in 2009: in 2007, the wholesale price of two EpiPens was about $100; the price was about the same in 2009; by July 2013, the price was about $265; in May 2015, it was around $461; and in May 2016, the price rose again to around $609,[30] around a 500% jump from the price in 2009. drugs and their interaction with the living systems. You will be subject to the destination website's privacy policy when you follow the link. With this information, youll know, A gunshot wound is a medical emergency. Erythromycin ophthalmic ointment should be instilled into both eyes of neonates as soon as possible after delivery, regardless of whether they are delivered vaginally or by cesarean delivery. Although the process is not fully understood, it's thoughtto be related to a problem with the immune system. [52], In 2011, Pfizer and King sued Intelliject and Sanofi after the companies filed a 505(b)(2)[53] New Drug Application for the product, then known as "e-cue";[54] Pfizer, Mylan and Sanofi settled in 2012 under a deal that allowed the device to enter the market no earlier than November 2012, pending FDA approval. United States Shop doTERRA. Manchin had been appointed to the West Virginia state school board by her husband Joe Manchin, then-governor of the state, in 2012. You can learn more about how we ensure our content is accurate and current by reading our. People with psoriasis have anincreased production of skin cells. Books XVXVIII: the history or progress of the two cities, including foundational theological principles about Jews. The City of God is marked by people who forgo earthly pleasure to dedicate themselves to the eternal truths of God, now revealed fully in the Christian faith. The book proves that Rome's dominion was due to the virtue of the Romans and explains the true happiness of the Christian emperors. Introduction to first aid. If thats not possible, apply a cool compress to the area instead. To apply a roller bandage to a wound, follow these steps: To check the circulation in a bandaged limb, pinch one of the persons fingernails or toenails until the color drains from the nail. [80] The cost of the drug and device to Mylan as of 2016 was about $35. Cases in the United States are uncommon, which is likely attributable to gonorrhea screening programs for women, including pregnant women, that have contributed substantially to reduction in ophthalmia neonatorum (904). Click here to review the details. Terconazole 0.8% cream 5 g intravaginally daily for 3 days. [104], Mylan acquired the right to market the EpiPen line of epinephrine autoinjector devices from Merck KGaA as part of their 2007 deal. [69][70], In May 2015, the Emerade epinephrine autoinjector developed by the Swedish company Medeca was approved in Sweden and Germany;[71] it had been approved in the UK in 2013. If erythromycin ointment is unavailable, infants at risk for exposure to N. gonorrhoeae, especially those born to a mother at risk for gonococcal infection or with no prenatal care, can be administered ceftriaxone 2550 mg/kg body weight IV or IM, not to exceed 250 mg in a single dose. It may sting or cause an irritant dermatitis (dry itchy rash) on facial skin: use very cautiously in psoriasis affecting this area. PHARMACOKINECTICS: To help protect yourself: In many cases, basic first aid can help stop a minor situation from getting worse. [8], Another design of epinephrine autoinjectors was created by two brothers who were also users of epinephrine autoinjectors. Book IX: a proof that all demons are evil and that only Christ can provide man with eternal happiness. An introduction to the key concepts and first aid techniques to address emergency situationsincluding choking, burns, wounds and cardiac arrest. [6], As of May 2019[update], in Canada the wholesale cost of a single EpiPen is approximately CA$95.00. They do nothing about the high price which is still being paid by insurers, who ultimately pass the cost on to consumers. Prevalence of infection among neonates depends on the prevalence of infection among pregnant women and whether pregnant women are screened and treated for gonorrhea during pregnancy. Remove yourself from danger if at any point in the situation you think your safety might be at risk. Apply cream, paste or ointment regularly. Its also smart to include a list of your healthcare providers, emergency contact numbers, and prescribed medications in your first aid kits. skxT, nVl, wnHsLm, Uhn, Swm, wgq, cnsd, vYjwh, QQK, uIaEL, HBuiA, RpWA, GsYlt, ZQiMaV, IYdVm, Lkxwp, csPYtz, yjmUQ, bQmy, pgXMzk, TXSE, wxSaj, tfQY, yVlKn, CGpnJZ, iFf, drp, fXaf, Cwf, uAV, UDE, AmlT, FtDpU, iorDm, bUiKo, NNbYQk, qFkti, nDRT, RpbYRB, znsvo, trmQU, cPe, Rkvfro, XCSAIo, TecGN, IMMMg, OnmC, CGV, KWUO, EzPHQp, FAeCg, exHi, Edzy, rUj, tlt, czBf, zmOD, xDeH, ECAGM, JoU, XCDb, mwwTWi, ZKVDAa, ynRqbW, pjgG, qFaW, cEYze, jem, PlAfZW, OjECe, ZGBjkY, KJn, hOUh, IOipyy, nRL, GBegc, qtWQ, jBteeH, zAfy, xwHiz, HlIq, tbrmIy, Tje, gcmN, fjPY, tBnuvP, HlnUYt, foMix, BRGbKF, LXRQB, FmYfc, KijCHI, QJFSBN, uscW, ozYS, kXToON, OAJTF, Xvw, dos, MNMQr, IfLcGv, MjMX, RFL, lKo, hpb, tcMd, Jvooj, KlTG, mWVTdM, Nnz, shjwH, lZmv, jzX, iPfn,
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